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Fears grow over lab-bred flu

Scientists call for stricter biosafety measures for dangerous avian-influenza variants.

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On 20 December, the US National Science Advisory Board for Biosecurity (NSABB) released a statement outlining its recommendations to the authors of the two flu studies under review, and to the editors of the journals that are considering publishing them. The statement says: "Due to the importance of the findings to the public health and research communities, the NSABB recommended that the general conclusions highlighting the novel outcome be published, but that the manuscripts not include the methodological and other details that could enable replication of the experiments by those who would seek to do harm. The NSABB also recommended that language be added to the manuscripts to explain better the goals and potential public health benefits of the research, and to detail the extensive safety and security measures taken to protect laboratory workers and the public." In response, Science's Editor-in-Chief Bruce Alberts said: "Science editors will be evaluating how best to proceed. Our response will be heavily dependent upon the further steps taken by the US government to set forth a written, transparent plan to ensure that any information that is omitted from the publication will be provided to all those responsible scientists who request it, as part of their legitimate efforts to improve public health and safety." In response, Nature's Editor-in-Chief Philip Campbell said: "We have noted the unprecedented NSABB recommendations that would restrict public access to data and methods and recognise the motivation behind them. It is essential for public health that the full details of any scientific analysis of flu viruses be available to researchers. We are discussing with interested parties how, within the scenario recommended by NSABB, appropriate access to the scientific methods and data could be enabled."

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NSABB

Biosecurity Challenges of the Global Expansion of High Containment Biological Laboratories

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Responsible Research with Biological Select Agents and Toxins

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Butler, D. Fears grow over lab-bred flu. Nature 480, 421–422 (2011). https://doi.org/10.1038/480421a

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