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Organization: Archive Team

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Formed in 2009, the Archive Team (not to be confused with the archive.org Archive-It Team) is a rogue archivist collective dedicated to saving copies of rapidly dying or deleted websites for the sake of history and digital heritage. The group is 100% composed of volunteers and interested parties, and has expanded into a large amount of related projects for saving online and digital history.

History is littered with hundreds of conflicts over the future of a community, group, location or business that were "resolved" when one of the parties stepped ahead and destroyed what was there. With the original point of contention destroyed, the debates would fall to the wayside. Archive Team believes that by duplicated condemned data, the conversation and debate can continue, as well as the richness and insight gained by keeping the materials. Our projects have ranged in size from a single volunteer downloading the data to a small-but-critical site, to over 100 volunteers stepping forward to acquire terabytes of user-created data to save for future generations.

The main site for Archive Team is at archiveteam.org and contains up to the date information on various projects, manifestos, plans and walkthroughs.

This collection contains the output of many Archive Team projects, both ongoing and completed. Thanks to the generous providing of disk space by the Internet Archive, multi-terabyte datasets can be made available, as well as in use by the Wayback Machine, providing a path back to lost websites and work.

Our collection has grown to the point of having sub-collections for the type of data we acquire. If you are seeking to browse the contents of these collections, the Wayback Machine is the best first stop. Otherwise, you are free to dig into the stacks to see what you may find.

The Archive Team Panic Downloads are full pulldowns of currently extant websites, meant to serve as emergency backups for needed sites that are in danger of closing, or which will be missed dearly if suddenly lost due to hard drive crashes or server failures.

Collection: Archive Team: URLs

TIMESTAMPS

The Wayback Machine - https://web.archive.org/web/20240419160626/https://uba.academia.edu/silviawikinski

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silvia wikinski

Universidad de Buenos Aires, Pharmacology, School of Medicine, Faculty Member

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Papers

[Practical notes on locating and critically reading scientific bibliography to guide clinical decisions, with a focus on quantitative research]

PubMed, Jan 23, 2020

In clinical practice it is increasingly imperative to obtain updated information for decision mak... more In clinical practice it is increasingly imperative to obtain updated information for decision making. For health professionals, it is of great value to collect the experience that other workers in the disciplinary field have synthesized in the form of articles, reviews or different types of reports. Moreover, having tools that allow weighing the internal and external validity of the publications found, provides skills that today are essential for a clinical practice that guarantees patients the best standards of care. These notes are intended to guide readers in obtaining and assessing the information available for reasoned decision making.

Depresión y ansiedad: de la clínica al tratamiento farmacológico

Fisiopatogenia en Psiquiatría: ¿descubrimiento, construcción o descubrimiento + construcción? El “caso” de la depresión

El empleo de la literatura científica en la práctica clínica: cómo encontrar y leer críticamente la bibliografía para orientarnos en la toma de decisiones

Fil: Wikinski, Silvia Ines. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Oficina d... more

[Vulnerability]

Vertex (Buenos Aires, Argentina), Jul 1, 2017

Body mass index, waist circumference, insulin, and leptin plasma levels differentiate between clozapine-responsive and clozapine-resistant schizophrenia

Journal of Psychopharmacology, Jun 28, 2023

Background: Between 25% and 50% of patients suffering from treatment-resistant schizophrenia fail... more Background: Between 25% and 50% of patients suffering from treatment-resistant schizophrenia fail to achieve a clinical response with clozapine. The rapid identification and treatment of this subgroup of patients represents a challenge for healthcare practice. Aims: To evaluate the relationship between metabolic alterations and the clinical response to clozapine. Methods: A multicenter, observational, case–control study was performed. Patients diagnosed with schizophrenia treated with clozapine were eligible (minimum dose 400 mg/d for at least 8 weeks and/or clozapine plasma levels ⩾ 350 µg/mL). According to the Positive and Negative Syndrome Scale (PANSS) total score, patients were classified as clozapine-responsive (CR) (&lt;80 points) or clozapine non-responsive (CNR) (⩾80 points). Groups were compared based on demographic and treatment-related characteristics, together with body mass index (BMI), waist circumference, insulin, leptin, and C-reactive protein plasma levels. Plasma levels of clozapine and its main metabolite, nor-clozapine, were measured in all the participants. In addition, the potential relationship between PANSS scores and leptin or insulin plasma levels was assessed. Results: A total of 46 patients were included: 25 CR and 21 CNR. BMI and waist circumference, fasting insulin and leptin plasma levels were lower in the CNR group, while C-reactive protein was not different. Moreover, significant negative correlations were observed between PANSS positive and general psychopathology subscores, on one hand, and insulin and leptin plasma levels, on the other hand, as well as between PANSS negative subscores and leptin plasma levels. Conclusions: Our results suggest that the lack of metabolic effect induced by clozapine is associated with the lack of clinical response.

El tratamiento farmacológico en psiquiatría: indicaciones, esquemas terapéuticos y elementos para su aplicación racional

ABSTRACT Incluye bibliografía e índice

Tratamiento a largo plazo del trastorno por pánico: historia natural, cronicidad y factores asociados

Vertex, 1998

[Psychiatry and obesity]

Vertex, 2018

Comprar El Tratamiento Farmacológico en Psiquiatría | Silvia Wikinski | 9788479039851 | Panamericana

Http Www Libreriasaulamedica Com, 2005

Day hospital treatment for people with severe mental illness according to users' perspectives: what helps and what hinders recovery?

Journal of mental health (Abingdon, England), Jan 13, 2017

Scarce information is available about how users experience treatment at mental health day hospita... more Scarce information is available about how users experience treatment at mental health day hospitals, particularly in South America. To explore users' perspectives about elements of day hospital treatment that facilitate or hinder the recovery process in a mental health facility in Buenos Aires, Argentina. Semi-structured individual interviews (n = 8) and focus groups (n = 4) were carried out with a convenience sample of users of a mental health day hospital program based on a formulation, testing and redevelopment of propositions approach. Results were analyzed through grounded theory techniques. Categories indicating recovery were: starting to do things, being able to see themselves from a new perspective, mood improvement and changes in interpersonal relationships. Aspects facilitating recovery were: activities organized by the facility, the group approach, the care provided by facility workers and the physical environment. Hindering aspects were: heterogeneity of users in ter...

El Tratamiento Farmacológico en Psiquiatría

Mecanismo de acción de drogas psicotrópicas: métodos para su investigación

Vertex, 1997

Papel de los aminoácidos excitatorios en la neuropatología; Role of excitatory amino acids in neuropathology

Medicina (B. Aires), 1995

Base de dados : LILACS. Pesquisa : 161640 [Identificador único]. Referências encontradas : 1 [ref... more

Comparison between HET-CAM protocols and a product use clinical study for eye irritation evaluation of personal care products including cosmetics according to their surfactant composition

Food and Chemical Toxicology, 2021

The hen's egg test on chorioallantoic membrane (HET-CAM) is one of the most frequently used a... more The hen's egg test on chorioallantoic membrane (HET-CAM) is one of the most frequently used alternative tests for prediction of ocular irritation of cosmetic products. There are different HET-CAM protocols widely accepted, but there is no information about which of the protocols better correlates with the results obtained in product use clinical study under the conditions of use. Two Fix Time Methods (FTM) -Lüepke and the ICCVAM guideline - and two Reaction Time Methods (RTM) -ECVAM DBALM Prot. No. 47 and No. 96- were employed to test 18 cosmetic products. Simultaneously, they were evaluated by an ophthalmological clinical test. A unified classification system was used, and products were classified into four irritation levels: non-irritant, weak, moderate and severe irritant. The duration of use (rinse-off or leave-on), and the concentration and type of surfactants were taken into account in the analysis. All the products that were classified as non-irritant by any HET-CAM protocols were also safe in the product use clinical study. The product that was found to be non-safe in the product use clinical evaluation was also unsuitable by most of the HET-CAM protocols. These results were employed to develop an algorithm that allows selecting the appropriate HET-CAM protocol for each type of product to be tested.

Pharmacokinetics of a novel spot-on formulation of praziquantel for dogs

Veterinary Parasitology, 2017

Working memory training triggers delayed chromatin remodeling in the mouse corticostriatothalamic circuit

Progress in neuro-psychopharmacology & biological psychiatry, Jan 24, 2015

Working memory is a cognitive function serving goal-oriented behavior. In the last decade, workin... more Working memory is a cognitive function serving goal-oriented behavior. In the last decade, working memory training has been shown to improve performance and its efficacy for the treatment of several neuropsychiatric disorders has begun to be examined. Neuroimaging studies have contributed to elucidate the brain areas involved but little is known about the underlying cellular events. A growing body of evidence has provided a link between working memory and relatively long-lasting epigenetic changes. However, the effects elicited by working memory training at the epigenetic level remain unknown. In this study we establish an animal model of working memory training and explore the changes in histone H3 acetylation (H3K9,14Ac) and histone H3 dimethylation on lysine 27 (H3K27Me2) triggered by the procedure in the brain regions of the corticostriatothalamic circuit (prelimbic/infralimbic cortex (PrL/IL), dorsomedial striatum (DMSt) and dorsomedial thalamus (DMTh)). Mice trained on a spont...

Valproic acid differs in its in vitro effect on glutamic acid decarboxylase activity in neonatal and adult rat brain

General Pharmacology: The Vascular System, 1996

Effects of fluoxetine on CRF and CRF1 expression in rats exposed to the learned helplessness paradigm

Psychopharmacology, 2012

An enriched environment restores normal behavior while providing cytoskeletal restoration and synaptic changes in the hippocampus of rats exposed to an experimental model of depression

Neuroscience, 2009

[Practical notes on locating and critically reading scientific bibliography to guide clinical decisions, with a focus on quantitative research]

PubMed, Jan 23, 2020

In clinical practice it is increasingly imperative to obtain updated information for decision mak... more In clinical practice it is increasingly imperative to obtain updated information for decision making. For health professionals, it is of great value to collect the experience that other workers in the disciplinary field have synthesized in the form of articles, reviews or different types of reports. Moreover, having tools that allow weighing the internal and external validity of the publications found, provides skills that today are essential for a clinical practice that guarantees patients the best standards of care. These notes are intended to guide readers in obtaining and assessing the information available for reasoned decision making.

Depresión y ansiedad: de la clínica al tratamiento farmacológico

Fisiopatogenia en Psiquiatría: ¿descubrimiento, construcción o descubrimiento + construcción? El “caso” de la depresión

El empleo de la literatura científica en la práctica clínica: cómo encontrar y leer críticamente la bibliografía para orientarnos en la toma de decisiones

Fil: Wikinski, Silvia Ines. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Oficina d... more

[Vulnerability]

Vertex (Buenos Aires, Argentina), Jul 1, 2017

Body mass index, waist circumference, insulin, and leptin plasma levels differentiate between clozapine-responsive and clozapine-resistant schizophrenia

Journal of Psychopharmacology, Jun 28, 2023

Background: Between 25% and 50% of patients suffering from treatment-resistant schizophrenia fail... more Background: Between 25% and 50% of patients suffering from treatment-resistant schizophrenia fail to achieve a clinical response with clozapine. The rapid identification and treatment of this subgroup of patients represents a challenge for healthcare practice. Aims: To evaluate the relationship between metabolic alterations and the clinical response to clozapine. Methods: A multicenter, observational, case–control study was performed. Patients diagnosed with schizophrenia treated with clozapine were eligible (minimum dose 400 mg/d for at least 8 weeks and/or clozapine plasma levels ⩾ 350 µg/mL). According to the Positive and Negative Syndrome Scale (PANSS) total score, patients were classified as clozapine-responsive (CR) (&lt;80 points) or clozapine non-responsive (CNR) (⩾80 points). Groups were compared based on demographic and treatment-related characteristics, together with body mass index (BMI), waist circumference, insulin, leptin, and C-reactive protein plasma levels. Plasma levels of clozapine and its main metabolite, nor-clozapine, were measured in all the participants. In addition, the potential relationship between PANSS scores and leptin or insulin plasma levels was assessed. Results: A total of 46 patients were included: 25 CR and 21 CNR. BMI and waist circumference, fasting insulin and leptin plasma levels were lower in the CNR group, while C-reactive protein was not different. Moreover, significant negative correlations were observed between PANSS positive and general psychopathology subscores, on one hand, and insulin and leptin plasma levels, on the other hand, as well as between PANSS negative subscores and leptin plasma levels. Conclusions: Our results suggest that the lack of metabolic effect induced by clozapine is associated with the lack of clinical response.

El tratamiento farmacológico en psiquiatría: indicaciones, esquemas terapéuticos y elementos para su aplicación racional

ABSTRACT Incluye bibliografía e índice

Tratamiento a largo plazo del trastorno por pánico: historia natural, cronicidad y factores asociados

Vertex, 1998

[Psychiatry and obesity]

Vertex, 2018

Comprar El Tratamiento Farmacológico en Psiquiatría | Silvia Wikinski | 9788479039851 | Panamericana

Http Www Libreriasaulamedica Com, 2005

Day hospital treatment for people with severe mental illness according to users' perspectives: what helps and what hinders recovery?

Journal of mental health (Abingdon, England), Jan 13, 2017

Scarce information is available about how users experience treatment at mental health day hospita... more Scarce information is available about how users experience treatment at mental health day hospitals, particularly in South America. To explore users' perspectives about elements of day hospital treatment that facilitate or hinder the recovery process in a mental health facility in Buenos Aires, Argentina. Semi-structured individual interviews (n = 8) and focus groups (n = 4) were carried out with a convenience sample of users of a mental health day hospital program based on a formulation, testing and redevelopment of propositions approach. Results were analyzed through grounded theory techniques. Categories indicating recovery were: starting to do things, being able to see themselves from a new perspective, mood improvement and changes in interpersonal relationships. Aspects facilitating recovery were: activities organized by the facility, the group approach, the care provided by facility workers and the physical environment. Hindering aspects were: heterogeneity of users in ter...

El Tratamiento Farmacológico en Psiquiatría

Mecanismo de acción de drogas psicotrópicas: métodos para su investigación

Vertex, 1997

Papel de los aminoácidos excitatorios en la neuropatología; Role of excitatory amino acids in neuropathology

Medicina (B. Aires), 1995

Base de dados : LILACS. Pesquisa : 161640 [Identificador único]. Referências encontradas : 1 [ref... more

Comparison between HET-CAM protocols and a product use clinical study for eye irritation evaluation of personal care products including cosmetics according to their surfactant composition

Food and Chemical Toxicology, 2021

The hen's egg test on chorioallantoic membrane (HET-CAM) is one of the most frequently used a... more The hen's egg test on chorioallantoic membrane (HET-CAM) is one of the most frequently used alternative tests for prediction of ocular irritation of cosmetic products. There are different HET-CAM protocols widely accepted, but there is no information about which of the protocols better correlates with the results obtained in product use clinical study under the conditions of use. Two Fix Time Methods (FTM) -Lüepke and the ICCVAM guideline - and two Reaction Time Methods (RTM) -ECVAM DBALM Prot. No. 47 and No. 96- were employed to test 18 cosmetic products. Simultaneously, they were evaluated by an ophthalmological clinical test. A unified classification system was used, and products were classified into four irritation levels: non-irritant, weak, moderate and severe irritant. The duration of use (rinse-off or leave-on), and the concentration and type of surfactants were taken into account in the analysis. All the products that were classified as non-irritant by any HET-CAM protocols were also safe in the product use clinical study. The product that was found to be non-safe in the product use clinical evaluation was also unsuitable by most of the HET-CAM protocols. These results were employed to develop an algorithm that allows selecting the appropriate HET-CAM protocol for each type of product to be tested.

Pharmacokinetics of a novel spot-on formulation of praziquantel for dogs

Veterinary Parasitology, 2017

Working memory training triggers delayed chromatin remodeling in the mouse corticostriatothalamic circuit

Progress in neuro-psychopharmacology & biological psychiatry, Jan 24, 2015

Working memory is a cognitive function serving goal-oriented behavior. In the last decade, workin... more Working memory is a cognitive function serving goal-oriented behavior. In the last decade, working memory training has been shown to improve performance and its efficacy for the treatment of several neuropsychiatric disorders has begun to be examined. Neuroimaging studies have contributed to elucidate the brain areas involved but little is known about the underlying cellular events. A growing body of evidence has provided a link between working memory and relatively long-lasting epigenetic changes. However, the effects elicited by working memory training at the epigenetic level remain unknown. In this study we establish an animal model of working memory training and explore the changes in histone H3 acetylation (H3K9,14Ac) and histone H3 dimethylation on lysine 27 (H3K27Me2) triggered by the procedure in the brain regions of the corticostriatothalamic circuit (prelimbic/infralimbic cortex (PrL/IL), dorsomedial striatum (DMSt) and dorsomedial thalamus (DMTh)). Mice trained on a spont...

Valproic acid differs in its in vitro effect on glutamic acid decarboxylase activity in neonatal and adult rat brain

General Pharmacology: The Vascular System, 1996

Effects of fluoxetine on CRF and CRF1 expression in rats exposed to the learned helplessness paradigm

Psychopharmacology, 2012

An enriched environment restores normal behavior while providing cytoskeletal restoration and synaptic changes in the hippocampus of rats exposed to an experimental model of depression

Neuroscience, 2009