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(+)-matrine (Q6787831)

From Wikidata
chemical compound
  • matrine
  • (7aS,13aR,13bR,13cS)-dodecahydro-1H,5H,10H-dipyrido[2,1-f:3′,2′,1′-ij][1,6]naphthyridin-10-one
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    English
    (+)-matrine
    chemical compound
    • matrine
    • (7aS,13aR,13bR,13cS)-dodecahydro-1H,5H,10H-dipyrido[2,1-f:3′,2′,1′-ij][1,6]naphthyridin-10-one

    Statements

    chemical structure
    BERJAYA
    Matrine.svg
    816 × 752; 3 KB
    0 references
    chemical formula
    C₁₅H₂₄N₂O
    1 reference
    stated in
    PubChem
    canonical SMILES
    C1CC2C3CCCN4C3C(CCC4)CN2C(=O)C1
    1 reference
    stated in
    PubChem
    isomeric SMILES
    O=C1CCC[C@@H]2[C@H]3CCCN4CCC[C@@H](CN12)[C@@H]34
    0 references
    found in taxon
    Sophora flavescens
    18 references
    stated in
    Alkaloid-Bearing Plants and Their Contained Alkaloids. 1957-1968
    stated in
    Variation and significance of microtubules in rat volume overload cardiac hypertrophy
    stated in
    Preparative separation of alkaloids from the root of Sophora flavescens Ait by pH-zone-refining counter-current chromatography
    stated in
    Lupin alkaloids in tissue culture of Sophora flavescens var. angustifolia: Greening induced production of matrine.
    stated in
    (-)-5alpha-Hydroxysophocarpine, a New Lupin Alkaloid from the Seeds of Sophora flavescens var. angustifolia1
    stated in
    Anticancer effects of the Chinese medicine matrine on murine hepatocellular carcinoma cells
    stated in
    Alkaloids from Sophora flavescens Aition
    stated in
    On the contractile response of fundus strip from rats to matrine, an alkaloidal component of Sophora flavescens
    stated in
    Separation of Alkaloids from Datura Metel. and Sophora Flavescens Ait by High-Speed Countercurrent Chromatography
    stated in
    Nematicidal activity of matrine and its derivatives against pine wood nematodes
    stated in
    Determination of quinolizidine alkaloids in traditional Chinese herbal drugs by nonaqueous capillary electrophoresis
    stated in
    Determination of alkaloids inSophora flavescens ait. andSophora viciifolia Hance by capillary zone electrophoresis
    stated in
    Supercritical fluid extraction of quinolizidine alkaloids from Sophora flavescens Ait. and purification by high-speed counter-current chromatography
    stated in
    Liquid chromatography of active principles in Sophora flavescens root
    stated in
    In Vitro Anti‐Tumour Activities of Quinolizidine Alkaloids Derived from Sophora Flavescens Ait
    stated in
    Matrine induces programmed cell death and regulates expression of relevant genes based on PCR array analysis in C6 glioma cells
    stated in
    Matrine inhibits the activity of translation factor eIF4E through dephosphorylation of 4E-BP1 in gastric MKN45 cells.
    stated in
    Matrine induces apoptosis in gastric carcinoma cells via alteration of Fas/FasL and activation of caspase-3.
    mass
    248.188863388 dalton
    1 reference
    based on heuristic
    inferred from SMILES
    Commons category
    Matrine
    0 references

    Identifiers

    ChemSpider ID
    82591
    0 references
    MassBank accession ID
    NSC number
    146051
    0 references
    318810
    0 references
    EC number
    610-750-6
    1 reference
    stated in
    ECHA Substance Infocard database
    ECHA Substance Infocard ID
    100.117.486
    retrieved
    27 December 2018
    title
    (7aS,13aR,13bR,13cS)-dodecahydro-1H,5H,10H-dipyrido[2,1-f:3′,2′,1′-ij][1,6]naphthyridin-10-one (English)
    quotation
    CAS no.: 519-02-8 (English)
    ECHA Substance Infocard ID
    100.117.486
    1 reference
    stated in
    ECHA Substance Infocard database
    ECHA Substance Infocard ID
    100.117.486
    retrieved
    27 December 2018
    title
    (7aS,13aR,13bR,13cS)-dodecahydro-1H,5H,10H-dipyrido[2,1-f:3′,2′,1′-ij][1,6]naphthyridin-10-one (English)
    quotation
    CAS no.: 519-02-8 (English)
    Freebase ID
    /m/0bs8xfy
    0 references
     
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