Respiratory Syncytial Virus Infection

“…Data analysis showed that both flu and RSV outbreaks were associated with MAARI-related surges in advanced medical outcomes in adults during the study years. Increases in MAARI-related advanced medical outcomes related to flu outbreaks have been apparent in the past for reasons reported by others [17][18][19][20]. Our results are similar to recently reported findings that revealed increases in MAARI-related advanced medical outcomes during RSV outbreaks [4,11,15].…”

“…Data from other states or regions may show different outcomes because of geographic, climate, and demographic variances. Previous studies have used MAARI-related data to quantify the occurrence and frequency of acute respiratory illnesses [16,17,20,22,29,30]. Based on our study, MAARI-related data also appear to be useful in assessing the degree of influence on advanced medical outcomes during both RSV and flu outbreaks.…”

“…Although we found a similar epidemic seasonal pattern, a proper time-series analysis is needed to draw robust conclusions as the mentioned authors Around the world, 1-3% of healthy children are hospitalized as result of RSV respiratory infections during the first year of life. 2,3,6,27 In our study, although most patients were healthy A C C E P T E D children younger than one year of age, patients with underlying conditions such as prematurity, congenital heart disease, malnutrition and chronic neurologic disease showed higher rates of mortality [28][29] . In a meta-analysis on incidence and mortality of RSV infections in children, Stein et al concluded that the virus was an important cause of hospitalization and mortality, and that gestational age was a critical determinant of disease severity in the first year of life 30 .…”

“…Our results also suggest that we captured the tail of an RSV outbreak in this population while the cohort size was small but increasing (due to rolling enrollment), and while enrolled infants were no more than 2 months of age. Nonetheless, we detected RSV in approximately 2% of study mothers during this short window, highlighting the potential importance of caregivers in RSV transmission ( Walsh, 2017 ).…”

“…Data analysis showed that both flu and RSV outbreaks were associated with MAARI-related surges in advanced medical outcomes in adults during the study years. Increases in MAARI-related advanced medical outcomes related to flu outbreaks have been apparent in the past for reasons reported by others [17][18][19][20]. Our results are similar to recently reported findings that revealed increases in MAARI-related advanced medical outcomes during RSV outbreaks [4,11,15].…”

“…Data from other states or regions may show different outcomes because of geographic, climate, and demographic variances. Previous studies have used MAARI-related data to quantify the occurrence and frequency of acute respiratory illnesses [16,17,20,22,29,30]. Based on our study, MAARI-related data also appear to be useful in assessing the degree of influence on advanced medical outcomes during both RSV and flu outbreaks.…”

“…Although we found a similar epidemic seasonal pattern, a proper time-series analysis is needed to draw robust conclusions as the mentioned authors Around the world, 1-3% of healthy children are hospitalized as result of RSV respiratory infections during the first year of life. 2,3,6,27 In our study, although most patients were healthy A C C E P T E D children younger than one year of age, patients with underlying conditions such as prematurity, congenital heart disease, malnutrition and chronic neurologic disease showed higher rates of mortality [28][29] . In a meta-analysis on incidence and mortality of RSV infections in children, Stein et al concluded that the virus was an important cause of hospitalization and mortality, and that gestational age was a critical determinant of disease severity in the first year of life 30 .…”

“…Our results also suggest that we captured the tail of an RSV outbreak in this population while the cohort size was small but increasing (due to rolling enrollment), and while enrolled infants were no more than 2 months of age. Nonetheless, we detected RSV in approximately 2% of study mothers during this short window, highlighting the potential importance of caregivers in RSV transmission ( Walsh, 2017 ).…”

“…Data analysis showed that both flu and RSV outbreaks were associated with MAARI-related surges in advanced medical outcomes in adults during the study years. Increases in MAARI-related advanced medical outcomes related to flu outbreaks have been apparent in the past for reasons reported by others [17][18][19][20]. Our results are similar to recently reported findings that revealed increases in MAARI-related advanced medical outcomes during RSV outbreaks [4,11,15].…”

“…Data from other states or regions may show different outcomes because of geographic, climate, and demographic variances. Previous studies have used MAARI-related data to quantify the occurrence and frequency of acute respiratory illnesses [16,17,20,22,29,30]. Based on our study, MAARI-related data also appear to be useful in assessing the degree of influence on advanced medical outcomes during both RSV and flu outbreaks.…”

“…Although we found a similar epidemic seasonal pattern, a proper time-series analysis is needed to draw robust conclusions as the mentioned authors Around the world, 1-3% of healthy children are hospitalized as result of RSV respiratory infections during the first year of life. 2,3,6,27 In our study, although most patients were healthy A C C E P T E D children younger than one year of age, patients with underlying conditions such as prematurity, congenital heart disease, malnutrition and chronic neurologic disease showed higher rates of mortality [28][29] . In a meta-analysis on incidence and mortality of RSV infections in children, Stein et al concluded that the virus was an important cause of hospitalization and mortality, and that gestational age was a critical determinant of disease severity in the first year of life 30 .…”

“…Our results also suggest that we captured the tail of an RSV outbreak in this population while the cohort size was small but increasing (due to rolling enrollment), and while enrolled infants were no more than 2 months of age. Nonetheless, we detected RSV in approximately 2% of study mothers during this short window, highlighting the potential importance of caregivers in RSV transmission ( Walsh, 2017 ).…”