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2014
DOI: 10.1111/1574-6976.12079
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Ribosomally encoded antibacterial proteins and peptides fromPseudomonas

Abstract: Members of the Pseudomonas genus produce diverse secondary metabolites affecting other bacteria, fungi or predating nematodes and protozoa but are also equipped with the capacity to secrete different types of ribosomally encoded toxic peptides and proteins, ranging from small microcins to large tailocins. Studies with the human pathogen Pseudomonas aeruginosa have revealed that effector proteins of type VI secretion systems are part of the antibacterial armamentarium deployed by pseudomonads. A novel class of … Show more

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Cited by 225 publications

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“…NBs with a tRNase cytotoxic domain were not identified outside of P . aeruginosa species which is in line with previous analysis [ 44 ] ( S8 Fig ). Many of the species observed were represented in the database by only a single genome suggesting the true extent of the sequence diversity within Pseudomonas spp.…”
Section: Results
supporting
confidence: 93%
“…Klebsiella pneumoniae genomes commonly encode a DNase bacteriocin as well as cloacin, a rRNase bacteriocin. This trend has also been observed in Pseudomonas species [ 44 ]. A similar distribution is observed with Yersinia mollaretii genomes where 4 isolates contained both DNase and rRNase NBs.…”
Section: Results
supporting
confidence: 76%
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