PPAPDC1A

PLPP4
Identifiers
Aliases	PLPP4, DPPL2, PPAPDC1, PPAPDC1A, phospholipid phosphatase 4
External IDs	MGI: 2685936; GeneCards: PLPP4
Enzyme activity
Gene location (Human)
Chr.	Chromosome 10 (human)
End	120,592,065 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	128,993,136 bp
RNA expression pattern
	Top expressed in
	oocyte; ; secondary oocyte; ; hypothalamus; ; hippocampus proper; ; substantia nigra; ; C1 segment; ; amygdala; ; pons; ; stromal cell of endometrium; ; putamen;
	Top expressed in
	olfactory bulb; ; hypothalamus; ; embryo; ; embryo; ; dentate gyrus of hippocampal formation granule cell; ; mesencephalon; ; cerebellum; ; cerebellar cortex; ; striatum of neuraxis; ; primary visual cortex;
	More reference expression data
	n/a
Gene ontology
Molecular function	hydrolase activity; phosphatidate phosphatase activity; identical protein binding; phosphatase activity;
Cellular component	integral component of membrane; plasma membrane; integral component of plasma membrane; membrane;
Biological process	phospholipid metabolic process; phospholipid dephosphorylation; Fc-gamma receptor signaling pathway involved in phagocytosis; signal transduction; blastocyst hatching;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	196051
	381925
	ENSG00000203805
	ENSMUSG00000070366
	Q5VZY2
	Q0VBU9
	NM_001030059; NM_001318166; NM_001318167; NM_001318168; NM_001318169
	NM_001080963
	NP_001025230; NP_001305095; NP_001305096; NP_001305097; NP_001305098
	NP_001074432
	Wikidata
View/Edit Human	View/Edit Mouse

Phosphatidate phosphatase PPAPDC1A also known as phosphatidic acid phosphatase type 2 domain containing 1A is an enzyme that in humans is encoded by the PPAPDC1A gene.^[5] PPAPDC1A has phosphatidate phosphatase activity.^[6]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000203805 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000070366 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: phosphatidic acid phosphatase type 2 domain containing 1A".
↑ Takeuchi M, Harigai M, Momohara S, Ball E, Abe J, Furuichi K, Kamatani N (September 2007). "Cloning and characterization of DPPL1 and DPPL2, representatives of a novel type of mammalian phosphatidate phosphatase". Gene. 399 (2): 174–80. doi:10.1016/j.gene.2007.05.009. PMID 17590538.

This article on a gene on human chromosome 10 is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000203805 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000070366 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: phosphatidic acid phosphatase type 2 domain containing 1A".

[pmid17590538-6] Takeuchi M, Harigai M, Momohara S, Ball E, Abe J, Furuichi K, Kamatani N (September 2007). "Cloning and characterization of DPPL1 and DPPL2, representatives of a novel type of mammalian phosphatidate phosphatase". Gene. 399 (2): 174–80. doi:10.1016/j.gene.2007.05.009. PMID 17590538.

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