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Cyproteronacetate in the management of severe acne in males

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Summary

We report the results of an investigation of the antiandrogen cyproteronacetate (Androcur) in the management of acne vulgaris in the male patient. The interim report covers our experiences with 11 patients treated with an orally administered dose of 25 mg cyproteronacetate. Marked improvement was noticed in most instances. Side effects were minimal. This study shows that cyproteronacetate is an effective agent in the control of recalcitrant acne in males.

Zusammenfassung

Wir berichten über die Untersuchungsergebnisse mit dem Antiandrogen Cyproteronacetat (Androcur) hinsichtlich der therapeutischen Beeinflussung von Akne bei männlichen Individuen. Die vorliegende Studie umfaßt 11 männliche Individuen, die mit einer täglichen Dosis von 25 mg Cyproteronacetat oral behandelt wurden. In den meisten Fällen konnte eine deutliche Besserung festgestellt werden. Die Nebenwirkungen waren minimal. Diese Untersuchung zeigt, daß Cyproteronacetat ein wirksames Mittel zur Behandlung von hartnäckiger Akne beim Manne ist.

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Cormane, R.H., van der Meeren, H.L.M. Cyproteronacetate in the management of severe acne in males. Arch Dermatol Res 271, 183–187 (1981). https://doi.org/10.1007/BF00412545

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